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Nitrogen mustard compounds

Nitrogen mustards are cytotoxic organic compounds with the chloroethylamine functional group, which consists of the following structure: Cl(CH2)2NR2, where R can be any organic group. They are nitrogen analogs of mustard gas.
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Keyword Search:
106 – 120 of 188 results
106

Medchemexpress LLC Vu0467485 (AZ13713945) | 1451994-10-7 | 99.3% | 10 MG
SDP

VU0467485 (AZ13713945) is a potent, selective, orally bioavailable positive allosteric modulator (PAM) of the muscarinic acetylcholine receptor M4 supplied as a solid research reagent for preclinical studies.

  • Potent and selective M4 receptor positive allosteric modulator.
  • Orally bioavailable in preclinical models.
  • High purity solid suitable for research applications.
  • Provided in small milligram pack sizes for preclinical dosing.
  • Molecular formula C17H17FN4O2S; molecular weight 360.41 g/mol.

ENCOMPASS_PREFERRED
107

Aobchem 1-(1-Chloroethyl)-2-fluorobenzene | 95% | CAS 60907-87-1 | C8H8ClF | 250mg

1-(1-Chloroethyl)-2-fluorobenzene | 95% | CAS 60907-87-1 | C8H8ClF | 250mg

ENCOMPASS_PREFERRED
108

Aobchem 1-(1-Chloroethyl)-2-fluorobenzene | 95% | CAS 60907-87-1 | C8H8ClF | 500mg

1-(1-Chloroethyl)-2-fluorobenzene | 95% | CAS 60907-87-1 | C8H8ClF | 500mg

ENCOMPASS_PREFERRED
109

Medchemexpress LLC Metarrestin | 1443414-10-5 | 99.9% | 25MG
SDP

Metarrestin | 1443414-10-5 | 99.9% | 25MG

ENCOMPASS_PREFERRED
110

Medchemexpress LLC Beta-catenin-IN-2 | 1458664-10-2 | 99.55% | 255.29 | 100 MG
SDP

Beta-catenin-IN-2 (Compound H1B1) is a potent β-catenin inhibitor used for the study of colorectal cancer. It suppresses the transcriptional activity of β-catenin/Tcf-4 in HCT116 cells in a dose-dependent manner at concentrations of 10-40 μM. The product is a solid, pink to red in color. It is soluble in DMSO at 83.33 mg/mL (326.41 mM).

  • Potent β-catenin inhibitor
  • Suppresses transcriptional activity of β-catenin/Tcf-4
  • Used for the study of colorectal cancer
  • Solid, pink to red in color
  • Soluble in DMSO

ENCOMPASS_PREFERRED
111

Medchemexpress LLC ML-184 25mg | 794572-10-4 | 470.63 g·mol⁻¹ | C25H34N4O3S | 25 MG
SDP

ML-184 is a small-molecule research compound described as a GPR55 agonist and used in cell-based and pharmacological studies. It is supplied as a high-purity solid for laboratory research and is identified by CAS 794572-10-4.

  • Acts as a GPR55 agonist for pharmacology and cell studies.
  • High reported purity suitable for research applications.
  • Molecular formula C25H34N4O3S and molecular weight 470.63 g·mol⁻¹.
  • Supplied as a solid in a 25 mg package for benchtop use.
  • CAS number 794572-10-4 provides an unambiguous chemical identifier.

ENCOMPASS_PREFERRED
112

Aobchem N-(2-Chloroethyl)-4-fluorobenzamide | ≥95% | CAS 15258-01-2 | C9H9ClFNO | 500mg

N-(2-Chloroethyl)-4-fluorobenzamide | ≥95% | CAS 15258-01-2 | C9H9ClFNO | 500mg

ENCOMPASS_PREFERRED
113

Medchemexpress LLC VIT-2763 | 2095668-10-1 | 99.9% | 408.43 | 50 MG
SDP

VIT-2763 is an oral ferroportin inhibitor designed to inhibit hepcidin binding to ferroportin and block iron efflux. It holds potential for treating β-thalassemia by addressing iron regulation. This compound has demonstrated significant biological activity both in vitro and in vivo.

  • Reduces fluorescence polarization signal by displacing TMR-hepcidin from ferroportin.
  • Induces BLA reporter gene activity, increasing intracellular iron concentrations by blocking iron export.
  • Triggers ubiquitination and degradation of ferroportin.
  • Corrects anemia and improves red blood cell parameters in relevant animal models.
  • Decreases the percentage of ROS-positive red blood cells and extends their lifespan.
  • Significantly decreases serum iron levels in animal studies.
  • Currently undergoing Phase 2 clinical trials for Beta-Thalassemia and Sickle Cell Disease.

ENCOMPASS_PREFERRED
114

Medchemexpress LLC HADA hydrochloride | 2253733-10-5 | 98.0% | 50 MG
SDP

HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue fluorescent D-amino acid (FDAA) with an emission wavelength of approximately 450 nm. It is efficiently incorporated into the peptidoglycans (PGs) of various bacterial species at the sites of PG biosynthesis. This allows for specific and covalent probing of bacterial growth with minimal perturbation.

  • Allows specific probing of bacterial growth.
  • Permits covalent probing of bacterial growth.
  • Causes minimal perturbation during bacterial growth probing.
  • Can be used for diverse bacterial species.

ENCOMPASS_PREFERRED
115

Medchemexpress LLC KB-5492 (anhydrous) | 129200-10-8 | 99.5% | 546.57 | 5 MG
SDP

KB-5492 anhydrous is a potent and selective inhibitor of the sigma receptor, inhibiting specific [3H]1,3-di(2-tolyl)guanidine (DTG) binding with an IC50 of 3.15 μM. It also functions as an anti-ulcer agent, preventing ethanol- and acidified aspirin-induced increases in 51Cr release from gastric epithelial cells in vitro, and macroscopic lesions in the gastric mucosa in vivo.

  • Potent and selective sigma receptor inhibitor
  • Inhibits specific DTG binding in a concentration-dependent manner
  • Prevents ethanol- and acidified aspirin-induced increases in 51Cr release from gastric epithelial cells
  • Prevents macroscopic lesions in the gastric mucosa in animal models
  • Suitable for research use only

ENCOMPASS_PREFERRED
116

eMolecules​ 915923-10-3 | N-(3-BROMOBENZYL)PROPANAMIDE | AstaTech | MFCD08569829 | 242.116 | C10H12BrNO | 95.000 | CCC(=O)NCc1cccc(Br)c1 | 1g | 268499194

N-(3-BROMOBENZYL)PROPANAMIDE | AstaTech | 915923-10-3 | MFCD08569829 | 242.116 | C10H12BrNO | 95.000 | CCC(=O)NCc1cccc(Br)c1 | 1g | 268499194

ENCOMPASS_PREFERRED
117

eMolecules​ 177-10-6 | 1,4-Dioxaspiro[4.5]decane | Ambeed | MFCD00005409 | 142.198 | C8H14O2 | 97.000 | C1COC2(CCCCC2)O1 | 250mg | 600845560

1,4-Dioxaspiro[4.5]decane | Ambeed | 177-10-6 | MFCD00005409 | 142.198 | C8H14O2 | 97.000 | C1COC2(CCCCC2)O1 | 250mg | 600845560

ENCOMPASS_PREFERRED
118

eMolecules​ 20949-81-9 | Ambeed | 2-Phenylthiazole-4-carbaldehyde | 250mg | 521423047 | A211674 | MFCD02681934 | 189.23 | C10H7NOS

AbaChemScene | 6-Chloro-3-(trifluoromethyl)picolinonitrile | 250mg | 391100577 | CS-W022479 | 401590-41-8 | MFCD18261725 | 206.550 | C7H2ClF3N2

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119

Aobchem 1-(1-Chloroethyl)-4-(1-methylethyl)benzene | 95% | CAS 13372-43-5 | C11H15Cl | 500mg

1-(1-Chloroethyl)-4-(1-methylethyl)benzene | 95% | CAS 13372-43-5 | C11H15Cl | 500mg

ENCOMPASS_PREFERRED
120

Medchemexpress LLC 2-phenylaminoadenosine | 53296-10-9 | MFCD00055119 | 98.0% | 358.35 g/mol | C16H18N6O4 | 5 MG
SDP

CV1808 (2-phenylaminoadenosine) is a research-grade, non-selective A2 adenosine receptor agonist used in pharmacology and receptor-binding studies. It shows reported Ki values of 76 nM at the A2A receptor and 1,450 nM at the A3 receptor, has molecular formula C16H18N6O4 and molecular weight 358.35 g/mol, and is supplied as a solid with analytical purity around 98.0% for research use only.

  • Non-selective A2 adenosine receptor agonist
  • Reported Ki: A2A = 76 nM; A3 = 1,450 nM
  • Molecular formula C16H18N6O4; molecular weight 358.35 g/mol
  • Analytical purity approximately 98.0%
  • Supplied as a solid for laboratory research applications

ENCOMPASS_PREFERRED